AcceGen

Brief Introduction  to PBMCs Peripheral Blood Mononuclear Cells (PBMC), also called Human Mononuclear Cells from Peripheral Blood (HMNC-PB), are cells with a single, round nucleus that are collected from peripheral or circulating blood. These blood cells are a key component in the immune system to fight infections and disease, adapting to invaders. PBMCs respond selectively to the immune system and are a key component of human immunity. PBMCs are a mixed population of monocytes composed primarily of lymphocytes, including T cells, B cells, and natural killer (NK) cells.   PMBCs are also a rich source of monocytes, such as macrophages, dendritic cells. Further cell isolations are performed by selecting key protein surface markers such as CD4 +  (T helper cells), CD8 +  (cytotoxic T cells), CD14 +  (monocytes), etc.   PBMCs undergo characteristic changes in various disease states and represent a way to monitor disease progression and understand disease pathology. For example, using trans

The human respiratory system is composed of a network of tissues and organs that enable the body to absorb oxygen from the air as well as expel carbon dioxide and other waste gasses. These functions are supported by a variety of cells that aid in promoting epithelial homeostasis, preventing alveolar collapse, facilitating the exchange of gasses between the blood and the tissues, and ensuring that the lungs adjust properly to low atmospheric pressure. Primary cells taken directly from the respiratory tissue of a human subject can simulate in vivo conditions with a very high degree of accuracy and, for that reason, have granted researchers a number of insights into various lung diseases and related medical disorders.   Types of Respiratory System Cells The cells of the respiratory system can be grouped into three distinct categories. These are: ● Nasal cells  – These can be found in the mucosal epithelium of the nasal cavity. ● Bronchial/Tracheal cells  – Taken from the linings of the tr