AcceGen

  The Characteristics of COVID-19 Infection with Pneumonia COVID-19 has greatly threatened human health worldwide due to the rapid spread of SARS-CoV-2, high morbidity, and mortality[1]. The clinical manifestations and spread of COVID-19 are complex[2]. Common symptoms include fever, cough, shortness of breath, chest pain, generalized fatigue, fatigue, headache, myalgia, insomnia, and diarrhea, while laboratory and radiological findings include lymphocytopenia and ground-glass opacities on chest imaging [3, 4].   COVID-19 pandemic  is a global crisis that threatens our way of life[5]. As of June 2020, more than 350,000 people died from COVID-19. The global mortality rate of COVID-19 is about 7%, and the recovery rate is about 30%. Therefore, many doctors and scientists are working on coronavirus vaccines to overcome this disease.   Composition and Characteristics of Heparin Heparin  is the second most widely used drug in the world that h...

The Relationship between Breast Cancer and Breast Cancer Cells Breast cancer  is the leading cause of cancer death among women in developed countries[1]. The majority of breast cancer patients are over 50 years old. However, the result of new cases study shows that the number of breast cancer patients under 45 years old has exceeded 10%[2].   Currently, most of the breast cancer knowledge comes from in vivo and in vitro studies using  breast cancer cell lines  because they can provide unlimited amounts of homologous self-replicating material using simple but standard media[3]. Therefore, it is essential to know whether these cell lines can capture molecules well before obtaining any clinically relevant results.   Breast Cancer MDA-MB-series Cell Lines Establishment MDA-MB- series tumor cell lines were established from M. D. Anderson Hospital and Tumor Institute. They have created a total of 19 MDA-MB series of cell lines from female patients ...

Neurodegenerative Diseases and Microglia Neurodegenerative diseases , such as Alzheimer’s disease, Parkinson’s diseases, and so on, were referred to chronic and progressive loss of neurons in the brain and activation of microglia in brain cells[1]. The symptoms of neurodegenerative diseases include memory loss, impaired executive function, personality changes, and progressive inability to perform daily activities[2].   Microglia  are immune cells in the central nervous system that mediate neuroinflammatory responses, which could perform immune monitoring, antigen presentation, and secretory regulatory immune molecules[3].   However, excessive activation of microglia can severely damage brain tissue and cause various neurodegenerative diseases such as Alzheimer’s disease (AD)[4]. As shown in figure 1, the microglia are activated in neurodegenerative diseases and express a large number of immune mediators such as IL-1β, TNFα, ROS...